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November 01, 2003
Statistical Methods for Cost Effectiveness Evaluation
Author: Andy Briggs
ISBN: 1899040 72 2
Publisher: Office for Health Economics
Price £12.50
Health economic evaluation has come of age. Today many industrialized countries recognize the importance of cost-effectiveness evidence in decision making. and the liscencing of new medications. Whilst not currently a regulatory requirement, the emergence of organizations such as the National Institute for Clinical Excellence (NICE) in the UK, the Canadian Coordinating Office for Helath Technology Assessment (CCHOTA) and the Pharmaceutical Benefits Advisory Committee (PBAC) in Australia are part of a general trend towards using cost-effectiveness information to decide which health care interventions are to become part of routine clinical practice. The increased interest in cost-effectiveness means it is now common to find economic variables collected prospectively alongside clinical trials. Over the last decade, to cope with the many new statistical methods for health economic evaluation have been suggested; not all have stood the test of time. The recent nature of many developments means that not all have yet been captured in popular textbooks in this area and what was once considered acceptable in term of analysis may no longer be appropriate.
In this latest OHE book a collection of papers by acknowledged experts in trial-based health economic evaluation is presented with the aim of giving clear guidance on recent developments in statistical methods for health economic evaluation, together with the intuition behind those methods, but without detailed technical exposition.
To order go to OHE
Chapter 2: Statistical analysis of uncertainty in cost-effectiveness studies Chapter 3: Sample size calculations and their sensitivity to underlying assumptions Chapter 4: The decision making perspective of health economic evaluation is essentially Bayesian Chapter 5 Sample size calculations for cost effectiveness from a Bayesian perspective capturing the spirit of what the analyst is attempting to do Chapter 6: Approaches to cost analysis in the presence of censoring Chapter 7: Inter-country comparisons: the use of statistical tests of heterogeneity between groups
